Biostimulators

What are biostimulators?

 

Biostimulators are injectable treatments designed to stimulate the skin’s natural repair processes rather than add volume.

​

    • Exosomes are cell-derived vesicles that communicate with skin cells to boost regeneration, collagen production, and reduce inflammation.

​

    • Polynucleotides (PNs) are purified DNA fragments that improve hydration, reduce oxidative stress, and support extracellular matrix repair.

​

• Profhilo® is a purified, ultra-high concentration hyaluronic acid injectable that spreads evenly under the skin to remodel tissue rather than add volume. It stimulates collagen types I and III and elastin, improving skin texture, elasticity, and hydration over time. Profhilo® is ideal for the face, neck, décolleté, and hands.

 

These treatments are ideal for individuals seeking skin rejuvenation, improved texture, and overall skin quality.

 

​

 

Products we use

 

We use licensed, clinically validated exosome and polynucleotide formulations, handled and stored according to manufacturer guidelines to ensure maximum safety and efficacy.

 

We use only licensed Profhilo® products stored and administered according to manufacturer guidelines. Correct handling and injection technique are essential to ensure consistent, safe results.

 

​

 

How it works 

​

   • Exosomes promote cell-to-cell communication, activating fibroblasts and keratinocytes to repair and regenerate tissue.

​

   • Polynucleotides integrate into the dermis to stimulate collagen, elastin, and hyaluronic acid production, improving skin elasticity, hydration, and tone.

​

• Profhilo® is injected at 5 precise points on each side of the face using the BAP (Bio Aesthetic Points) technique. Once injected, the hyaluronic acid spreads under the skin, stimulating fibroblasts to increase collagen and elastin production. The result is gradual improvement in skin firmness, elasticity, and overall quality. Effects are cumulative and typically seen over multiple sessions.

 

Effects are cumulative and typically seen over several sessions.

 

​

 

Who is a good candidate?

• Adults with early ageing, fine lines, or dull, dehydrated skin

• Individuals with mild scarring, pigmentation issues, or skin laxity

• Not suitable if pregnant, breastfeeding, or with active infection at the injection site

 

​

 

Your clinic journey — what to expect

 

1. Consultation (essential)

• Comprehensive skin assessment and discussion of treatment goals

• Review of medical history, medications, and potential contraindications

 

2. Treatment appointment (typically 30–45 minutes)

• Skin cleansing and preparation

• Profhilo/Polynucleotides  - Microinjections using ultra-fine needles. Exosomes are combined with microneedling for enhanced absorption

• Minimal discomfort; topical anaesthetic applied if needed

 

3. Recovery & follow-up

• Mild redness or swelling may occur for 24–48 hours

• Progressive improvement in skin quality over 2–4 weeks

• Typically 3–4 sessions spaced 2–4 weeks apart for optimal results followed by maintenance sessions every 6-9 months.

​

 

​

 

Areas commonly treated

• Full face, neck, décolleté, and hands

• Under-eye area for dark circles or thin skin

• Mild scarring or textural irregularities

 

​

 

Aftercare — easy but important

• Avoid rubbing or massaging treated areas for 24–48 hours

• Avoid heat, alcohol, or strenuous exercise for 24 hours

• Mild redness, swelling, or small bumps are normal

 

​

 

Risks, side-effects & safety

• Common: temporary redness, swelling, minor bruising

• Rare: infection, allergic reaction, or asymmetry

• Treatments performed only by qualified medical practitioners using licensed products

 

​

 

Why choose a doctor led clinic

 

Medical assessment, anatomy-based injection technique, licensed product use, and structured follow-up ensure predictable, safe, and natural results.

 

​

 

FAQ 

 

Q: Does it hurt?

A: Most clients experience only mild discomfort; topical anaesthetic can be applied if needed.

 

Q: When will I see results and how long do they last?

A: Gradual improvements appear within 2–4 weeks; optimal results are cumulative over 3–4 sessions and can last 6–9 months with maintenance.

 

Q: Can it be combined with other treatments?

A: Yes. Biostimulators can be safely combined with neuromodulators, dermal fillers, Profhilo®, or microneedling.

 

Q: Is it safe long-term?

A: When administered by trained clinicians using licensed products, biostimulators have an excellent long-term safety profile.